منابع مشابه
PKD is for dense granule secretion.
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متن کاملThe actin cytoskeleton differentially regulates platelet -granule and dense-granule secretion
http://bloodjournal.hematologylibrary.org/content/105/10/3879.full.html Updated information and services can be found at: (1930 articles) Signal Transduction (2497 articles) Hemostasis, Thrombosis, and Vascular Biology (143 articles) Cytoskeleton Articles on similar topics can be found in the following Blood collections http://bloodjournal.hematologylibrary.org/site/misc/rights.xhtml#r...
متن کاملHEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY The actin cytoskeleton differentially regulates platelet -granule and dense-granule secretion
Stimulation of platelets with strong agonists results in centralization of cytoplasmic organelles and secretion of granules. These observations have led to the supposition that cytoskeletal contraction facilitates granule release by promoting the interaction of granules with one another and with membranes of the open canalicular system. Yet, the influence of the actin cytoskeleton in controllin...
متن کاملPlatelet dense granule secretion defects may obscure α-granule secretion mechanisms: evidence from Munc13-4-deficient platelets.
would have been missed. Further, ethnic differences in incidence trends have only been observed in childhoodALLand are not present in other childhood cancers (eg, childhood brain tumors), suggesting that changes in ethnic classification are unlikely to be solely responsible for trend differences. In utero exposure to factors such as tobacco are likely to have remained stable or decreased in pre...
متن کاملBacterial Production of Dense Granule Antigen GRA8 of Toxoplasma gondii
Background: Dense granule antigens (GRA antigens) of Toxoplasma gondii induce strong antibody response in humans and are considered as useful diagnostic antigens. Previous studies reported expression of amino terminal GRA8 protein in fusion with large tags such as glutathione-S-transferase. The present study aimed to produce soluble full length immunogenic GRA8 in bacteria. Methods: GRA8 comple...
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ژورنال
عنوان ژورنال: Blood
سال: 2011
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood-2011-05-352559